特別含有成分紹介

このサプリメントは必須ビタミン・アミノ酸と特別含有成分で作られています。特別含有成分に指摘されている一部効果と根拠論文の一部を掲載しています。

​カルニチン　　　　

・心臓の健康維持

Ferrari R, Merli E, Cicchitelli G, Mele D, Fucili A, Ceconi C. Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review. Ann N Y Acad Sci. 2004 Nov;1033:79-91. 

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Iliceto S, Scrutinio D, Bruzzi P, D'Ambrosio G, Boni L, Di Biase M, Biasco G, Hugenholtz PG, Rizzon P. Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial. J Am Coll Cardiol. 1995 Aug;26(2):380-7.

・運動パフォーマンスのサポート

Sahlin K. Boosting fat burning with carnitine: an old friend comes out from the shadow. J Physiol. 2011 Apr 1;589(Pt 7):1509-10.

・脳の健康維持、認知機能の維持

Rai G, Wright G, Scott L, Beston B, Rest J, Exton-Smith AN. Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia. Curr Med Res Opin. 1990;11(10):638-47.

Ando S, Tadenuma T, Tanaka Y, Fukui F, Kobayashi S, Ohashi Y, Kawabata T. Enhancement of learning capacity and cholinergic synaptic function by carnitine in aging rats. J Neurosci Res. 2001 Oct 15;66(2):266-71.

・血糖の調整

Galloway SD, Craig TP, Cleland SJ. Effects of oral L-carnitine supplementation on insulin sensitivity indices in response to glucose feeding in lean and overweight/obese males. Amino Acids. 2011 Jul;41(2):507-15.

・血圧の低下作用

Ruggenenti P, Cattaneo D, Loriga G, Ledda F, Motterlini N, Gherardi G, Orisio S, Remuzzi G. Ameliorating hypertension and insulin resistance in subjects at increased cardiovascular risk: effects of acetyl-L-carnitine therapy. Hypertension. 2009 Sep;54(3):567-74.

Miguel-Carrasco JL, Mate A, Monserrat MT, Arias JL, Aramburu O, Vázquez CM. The role of inflammatory markers in the cardioprotective effect of L-carnitine in L-NAME-induced hypertension. Am J Hypertens. 2008 Nov;21(11):1231-7.

・ダイエットのサポート

Talenezhad N, Mohammadi M, Ramezani-Jolfaie N, Mozaffari-Khosravi H, Salehi-Abargouei A. Effects of l-carnitine supplementation on weight loss and body composition: A systematic review and meta-analysis of 37 randomized controlled clinical trials with dose-response analysis. Clin Nutr ESPEN. 2020 Jun;37:9-23.

セレン

・抗酸化作用による発癌、虚血性心疾患、糖尿病リスクの低下

Fernandez E, Chatenoud L, La Vecchia C, Negri E, Franceschi S. Fish consumption and cancer risk. Am. J. Clin. Nutr. 70.85-90 (1999).

Mozaffarian D. Fish, mercury, selenium and cardiovascular risk: current evidence and unanswered questions. Int. J. Environ. Res. Public Health. 6. 1894-1916 (2009).

天然型Vit.D

・骨粗鬆症の予防

A. Avenell, J. C. S. Mak & D. O’Connell, The Cochrane Library, DOI: 10.1002/14651858.CD000227, Online Pub lication Date: April（2014）．

・心血管保護作用に伴う腎保護作用

Y. C. Li, J. Kong, M. Wei, Z. F. Chen, S. Q. Liu & L. P. Cao, J Clin Inves, 110, 229（2002）．

C. Zhou, F. Lu, K. Cao, D. Xu, D. Goltzman & D. Miao, Kidney Int, 74, 170（2008）．

J. Kong, G. Qiao, Z. Zhang, S. Q. Liu &Y. C. Li, Kidney Int, 74, 1577（2008）．

J. P. Forman, J. S. Williams & N. D. Fisher, Hyperten sion, 55, 1283（2010）．

・免疫・感染防御UP

M. Urashima, T. Segawa, M. Okazaki, M. Kurihara, Y. Wada & H Ida, Am J Clin Nutr, 91, 1255（2010）．

P. Bergman, A. C. Norlin, S. Hansen, R. S. Rekha, B. Agerberth, L. Björkhem-Bergman, L. Ekström, J. D. Lindh & J. Andersson, BMJ Open, 2, e001663（2012）．

重曹（炭酸水素ナトリウム）

・腎保護作用

de Brito-Ashurst I, et al:J Am Soc Nephrol. 2009;20(9):2075-84.

Mahajan A, et al:Kidney Int. 2010;78(3):303-9.

Vallet M, et al:Kidney Int. 2015;88(1):137-45.

Kurtz TW, et al:N Engl J Med. 1987;317(17): 1043-8.

Souma T, et al:J Am Soc Nephrol. 2011;22(4): 635-48.

葉酸

・臓器保護作用

The American Journal of Clinical Nutrition, Volume 86, Issue 3, September 2007, Pages 610–617,

Cancer Epidemiol Biomarkers Prev. 2013 Jan 10;22(3):415–421. 

・抗酸化作用

Environ Toxicol​　2009 Aug;24(4):377-87

Free Radic Biol Med​　2001 Jun 15;30(12):1390-9